A Bootstrap Based Measure Robust to the Choice of Normalization Methods for Detecting Rhythmic Features in High Dimensional Data

Motivation: Gene-expression data obtained from high throughput technologies are subject to various sources of noise and accordingly the raw data are pre-processed before formally analyzed. Normalization of the data is a key pre-processing step, since it removes systematic variations across arrays. T...

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Bibliographic Details
Main Authors: Yolanda Larriba, Cristina Rueda, Miguel A. Fernández, Shyamal D. Peddada
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00024/full