The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung

The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung

Pneumonia is one of the leading causes of death and mortality worldwide. The inflammatory responses that follow respiratory infections are protective leading to pathogen clearance but can also be deleterious if unregulated. The microbiota is known to be an important protective barrier against infect...

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Bibliographic Details
Main Authors: Izabela Galvão, Luciana P. Tavares, Renan O. Corrêa, José Luís Fachi, Vitor Melo Rocha, Marcela Rungue, Cristiana C. Garcia, Geovanni Cassali, Caroline M. Ferreira, Flaviano S. Martins, Sergio C. Oliveira, Charles R. Mackay, Mauro M. Teixeira, Marco Aurélio R. Vinolo, Angélica T. Vieira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
lung infection
GPR43
inflammation
microbiota
short-chain fatty acids
pneumonia
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00142/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00142/full

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