Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

<p>Abstract</p> <p>Background</p> <p>Alpha-defensins, which are major constituents of neutrophil azurophilic granules, and beta-defensins, which are expressed in airway epithelial cells, could contribute to the pathogenesis of chronic obstructive pulmonary disease by am...

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Bibliographic Details
Main Authors: Anthonisen Nicholas R, Connett John E, Ruan Jian, Burkett Kelly M, He Jian-Qing, Wallace Alison M, Paré Peter D, Sandford Andrew J
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/76