The HER2-encoded miR-4728-3p regulates ESR1 through a non-canonical internal seed interaction.

Since the early 1980s remarkable progress has been made in understanding the role of the HER2 locus in carcinogenesis, but many details of its regulatory network are still elusive. We recently reported the finding of 367 new human microRNA (miRNA) genes of which one, mir-4728, is encoded in an intro...

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Bibliographic Details
Main Authors: Inga Newie, Rolf Søkilde, Helena Persson, Dorthe Grabau, Natalia Rego, Anders Kvist, Kristoffer von Stedingk, Håkan Axelson, Åke Borg, Johan Vallon-Christersson, Carlos Rovira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020767?pdf=render