Endothelial Atg7 Deficiency Ameliorates Acute Cerebral Injury Induced by Ischemia/Reperfusion

Endothelial Atg7 Deficiency Ameliorates Acute Cerebral Injury Induced by Ischemia/Reperfusion

Ischemic strokes often result in cerebral injury due to ischemia/reperfusion (I/R). Although the local inflammatory responses are known to play a primary role in the brain I/R injury, the underlying mechanism remains unclear. In the current study, we investigated the effect of brain endothelial Atg7...

Full description

Bibliographic Details
Main Authors: Hui-Jie Wang, Jia-Yi Wei, Dong-Xin Liu, Shi-Fang Zhuang, Yuan Li, Hui Liu, Meng Ban, Wen-Gang Fang, Liu Cao, Wei-Dong Zhao, Yu-Hua Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neurology
Subjects:
Atg7
brain microvascular endothelial cells
ischemia/reperfusion injury
pro-inflammatory cytokines
transient focal cerebral ischemia
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00998/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00998/full

Similar Items