Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression

<p>Abstract</p> <p>Background</p> <p>NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have been associated with Cro...

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Bibliographic Details
Main Authors: Mathew Christopher G, Roberts Roland G, Platzer Cornelia, Reichwald Kathrin, Hampe Jochen, Franke Andre, Huse Klaus, Rosenstiel Philip, Platzer Matthias, Schreiber Stefan
Format: Article
Language:English
Published: BMC 2007-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/472