A New Ligustrazine Derivative-Selective Cytotoxicity by Suppression of NF-κB/p65 and COX-2 Expression on Human Hepatoma Cells. Part 3

A New Ligustrazine Derivative-Selective Cytotoxicity by Suppression of NF-κB/p65 and COX-2 Expression on Human Hepatoma Cells. Part 3

A new anticancer ligustrazine derivative, 3β-hydroxyolea-12-en-28-oic acid- 3,5,6-trimethylpyrazin-2-methylester (T-OA, C38H58O3N2), was previously reported. It was synthesized via conjugating hepatoprotective and anticancer ingredients of traditional Chinese medicine. We found that T-OA exerted its...

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Bibliographic Details
Main Authors: Chenze Zhang, Wenqiang Yan, Bi Li, Bing Xu, Yan Gong, Fuhao Chu, Yuzhong Zhang, Qiuli Yao, Penglong Wang, Haimin Lei
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
ligustrazine derivative
selective cytotoxicity
hepatoma
NF-κB/p65 and COX-2
Online Access:http://www.mdpi.com/1422-0067/16/7/16401

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http://www.mdpi.com/1422-0067/16/7/16401

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