Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

<p>Abstract</p> <p>Background</p> <p>Prior studies suggest a role for a variant (rs5743836) in the promoter of toll-like receptor 9 (TLR9) in asthma and other inflammatory diseases. We performed detailed genetic association studies of the functional variant rs5743836 wi...

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Main Authors: Celedón Juan C, Soto-Quirós Manuel, Avila Lydiana, Lazarus Ross, Himes Blanca E, Lasky-Su Jessica, Zhou Xiaobo, Lange Nancy E, Hawrylowicz Catherine M, Raby Benjamin A, Litonjua Augusto A
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/26

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http://www.biomedcentral.com/1471-2350/12/26

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