Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer

Abstract Hypopharyngeal squamous cell carcinoma (HPSCC) has a very poor prognosis. Local surgery may increase survival, but is often avoided due to significant post-op co-morbidities. Since prognostic markers are lacking, the aim was to find predictive biomarkers that identify patients whose respons...

Full description

Bibliographic Details
Main Authors: Michael Mints, David Landin, Anders Näsman, Leila Mirzaie, Ramona Gabriela Ursu, Mark Zupancic, Linda Marklund, Tina Dalianis, Eva Munck-Wikland, Torbjörn Ramqvist
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80226-z