Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease

Abstract Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods for reliable assessment of dopamine neuron maturation in vivo are lacking. Establishing the efficacy of new cellular therapies using non-invasive methodologies...

Full description

Bibliographic Details
Main Authors: Julian L. Goggi, Lifeng Qiu, Mei Chih Liao, Shivashankar Khanapur, Lingfan Jiang, Ramasamy Boominathan, Siddesh V. Hartimath, Peter Cheng, Fui Fong Yong, Vanessa Soh, Xiaozhou Deng, Youshan Melissa Lin, Anna Haslop, Peng Wen Tan, Xiaoxia Zeng, Jolene W. L. Lee, Zhiwei Zhang, Pragalath Sadasivam, Eng King Tan, Sajinder K. Luthra, William D. Shingleton, Steve K. W. Oh, Li Zeng, Edward G. Robins
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Parkinson’s disease
Dopaminergic neuron
Cell therapy
PET imaging
DAT
Online Access:http://link.springer.com/article/10.1186/s13287-020-01868-4

Internet

http://link.springer.com/article/10.1186/s13287-020-01868-4

Similar Items