Ellagic Acid Alleviates Hepatic Oxidative Stress and Insulin Resistance in Diabetic Female Rats

Ellagic Acid Alleviates Hepatic Oxidative Stress and Insulin Resistance in Diabetic Female Rats

Non-alcoholic fatty liver disease (NAFLD) affects more than 70% of patients with type 2 diabetes mellitus (T2DM) and has become one of the most common metabolic liver diseases worldwide. To date, treatments specifically targeting NAFLD do not exist. Oxidative stress and insulin resistance have been...

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Bibliographic Details
Main Authors: Simran Alexandria Polce, Cameron Burke, Lucas Martins França, Benjamin Kramer, Antonio Marcus de Andrade Paes, Maria Alicia Carrillo-Sepulveda
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Nutrients
Subjects:
Ellagic Acid
Goto-kakizaki (GK) rats
hepatic steatosis
insulin resistance
oxidative stress
HIF-α
p47-phox
NRF2
Type II Diabetes Mellitus (T2DM)
antioxidant
Online Access:http://www.mdpi.com/2072-6643/10/5/531

Internet

http://www.mdpi.com/2072-6643/10/5/531

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