Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

Microglia are the primary innate immune cell type in the brain, and their dysfunction has been linked to a variety of central nervous system disorders. Human microglia are extraordinarily difficult to obtain for experimental investigation, limiting our ability to study the impact of human genetic va...

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Bibliographic Details
Main Authors: Peter J. Amos, Susan Fung, Amanda Case, Jerusalem Kifelew, Leah Osnis, Carole L. Smith, Kevin Green, Alipi Naydenov, Macarena Aloi, Jesse J. Hubbard, Aravind Ramakrishnan, Gwenn A. Garden, Suman Jayadev
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/1759091417716610

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https://doi.org/10.1177/1759091417716610

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