Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum

Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum

The Tres Cantos Antimalarial Compound Set (TCAMS) is a publicly available compound library which contains 13533 hit structures with confirmed activity against Plasmodium falciparum, the infective agent responsible for malaria tropica. The TCAMS provides a variety of starting points for the investiga...

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Bibliographic Details
Main Authors: Thomas Weidner, Abed Nasereddin, Lutz Preu, Johann Grünefeld, Ron Dzikowski, Conrad Kunick
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
diarylether
luciferase
Malaria
2-phenoxyanilide
Plasmodium falciparum
TCAMS
TCMDC-137332
Online Access:http://www.mdpi.com/1420-3049/21/2/223

Internet

http://www.mdpi.com/1420-3049/21/2/223

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