PCR Array Technology in Biopsy Samples Identifies Up-Regulated mTOR Pathway Genes as Potential Rejection Biomarkers After Kidney Transplantation

PCR Array Technology in Biopsy Samples Identifies Up-Regulated mTOR Pathway Genes as Potential Rejection Biomarkers After Kidney Transplantation

Background: Antibody-mediated rejection (AMR) is the major cause of kidney transplant rejection. The donor-specific human leukocyte antigen (HLA) antibody (DSA) response to a renal allograft is not fully understood yet. mTOR complex has been described in the accommodation or rejection of transplants...

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Bibliographic Details
Main Authors: Isabel Legaz, María Victoria Bernardo, Rafael Alfaro, Helios Martínez-Banaclocha, Jose Antonio Galián, Victor Jimenez-Coll, Francisco Boix, Anna Mrowiec, Diego Salmeron, Carmen Botella, Antonio Parrado, María Rosa Moya-Quiles, Alfredo Minguela, Santiago Llorente, Jesús de la Peña-Moral, Manuel Muro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
mTOR
Gene expression
medico-legal autopsy
antibody-mediated rejection
PCR array
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.547849/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.547849/full

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