High fat feeding induces hepatic fatty acid elongation in mice.

High fat feeding induces hepatic fatty acid elongation in mice.

BACKGROUND:High-fat diets promote hepatic lipid accumulation. Paradoxically, these diets also induce lipogenic gene expression in rodent liver. Whether high expression of these genes actually results in an increased flux through the de novo lipogenic pathway in vivo has not been demonstrated. METHOD...

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Bibliographic Details
Main Authors: Maaike H Oosterveer, Theo H van Dijk, Uwe J F Tietge, Theo Boer, Rick Havinga, Frans Stellaard, Albert K Groen, Folkert Kuipers, Dirk-Jan Reijngoud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699051?pdf=render

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http://europepmc.org/articles/PMC2699051?pdf=render

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