Long-term Temozolomide Treatment Induces Marked Amino Metabolism Modifications and an Increase in TMZ Sensitivity in Hs683 Oligodendroglioma Cells

Long-term Temozolomide Treatment Induces Marked Amino Metabolism Modifications and an Increase in TMZ Sensitivity in Hs683 Oligodendroglioma Cells

Gliomas account for more than 50% of all primary brain tumors. The worst prognosis is associated with gliomas of astrocytic origin, whereas gliomas with an oligodendroglial origin offer higher sensitivity to chemotherapy, especially when oligodendroglioma cells display 1p19q deletions. Temozolomide...

Full description

Bibliographic Details
Main Authors: Delphine Lamoral-Theys, Marie Le Mercier, Benjamin Le Calvé, Michal A. Rynkowski, Céline Bruyère, Christine Decaestecker, Benjamin Haibe-Kains, Gianluca Bontempi, Jacques Dubois, Florence Lefranc, Robert Kiss
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800867

Internet

http://www.sciencedirect.com/science/article/pii/S1476558610800867

Similar Items