Human bone marrow-derived stromal cell behavior when injected directly into the bone marrow of NOD-scid-gamma mice pre-conditioned with sub-lethal irradiation

Abstract Background Direct bone marrow injection of cells into murine marrow cavities is used in a range of cell characterization assays and to develop disease models. While human bone marrow-derived stromal cells (hBMSC, also known as mesenchymal stem cells (MSC)) are frequently described in therap...

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Bibliographic Details
Main Authors: Bianca Nowlan, Kathryn Futrega, Elizabeth Deborah Williams, Michael Robert Doran
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-021-02297-7