t-Test at the Probe Level: An Alternative Method to Identify Statistically Significant Genes for Microarray Data

t-Test at the Probe Level: An Alternative Method to Identify Statistically Significant Genes for Microarray Data

Microarray data analysis typically consists in identifying a list of differentially expressed genes (DEG), i.e., the genes that are differentially expressed between two experimental conditions. Variance shrinkage methods have been considered a better choice than the standard t-test for selecting the...

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Bibliographic Details
Main Authors: Marcelo Boareto, Nestor Caticha
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Microarrays
Subjects:
microarrays
preprocessing
variance shrinkage
t-test
background correction
Online Access:http://www.mdpi.com/2076-3905/3/4/340

Internet

http://www.mdpi.com/2076-3905/3/4/340

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