Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections

Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections

We investigated whether chloroquine can prevent hantavirus infection and disease in vitro and in vivo, using the Hantaan virus newborn C57BL/6 mice model and the Syrian hamster model for Andes virus. In vitro antiviral experiments were performed using Vero E6 cells, and Old World and New World hanta...

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Bibliographic Details
Main Authors: Valentijn Vergote, Lies Laenen, Raf Mols, Patrick Augustijns, Marc Van Ranst, Piet Maes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
hantavirus
Andes virus
prophylactic treatment
osmotic pump
Syrian hamster animal model
chloroquine (CQ)
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.580532/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.580532/full

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