CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria
Hypoxia is a characteristic of the tumor microenvironment and is known to contribute to tumor progression and treatment resistance. Hypoxia-inducible factor (HIF) dimeric transcription factors control the cellular response to reduced oxygenation by regulating the expression of genes involved in meta...
Main Authors: | Luke W. Thomas, Oliver Staples, Mark Turmaine, Margaret Ashcroft |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-04-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2017.00071/full |
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