Improved in vitro culture of Plasmodium falciparum permits establishment of clinical isolates with preserved multiplication, invasion and rosetting phenotypes.

Improved in vitro culture of Plasmodium falciparum permits establishment of clinical isolates with preserved multiplication, invasion and rosetting phenotypes.

To be able to robustly propagate P. falciparum at optimal conditions in vitro is of fundamental importance for genotypic and phenotypic studies of both established and fresh clinical isolates. Cryo-preserved P. falciparum isolates from Ugandan children with severe or uncomplicated malaria were inves...

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Main Authors: Ulf Ribacke, Kirsten Moll, Letusa Albrecht, Hodan Ahmed Ismail, Johan Normark, Emilie Flaberg, Laszlo Szekely, Kjell Hultenby, Kristina E M Persson, Thomas G Egwang, Mats Wahlgren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3718792?pdf=render

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http://europepmc.org/articles/PMC3718792?pdf=render

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