Fatal thoracic aortic aneurysm and dissection in a large family with a novel MYLK gene mutation: delineation of the clinical phenotype

Fatal thoracic aortic aneurysm and dissection in a large family with a novel MYLK gene mutation: delineation of the clinical phenotype

Abstract Background Thoracic and abdominal aortic aneurysms and dissection often develop in hypertensive elderly patients. At higher risk are smokers and those who have a family history of aortic aneurysms. In most affected families, the aortic aneurysms and dissection is inherited in an autosomal d...

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Bibliographic Details
Main Authors: Adel Shalata, Mohammad Mahroom, Dianna M. Milewicz, Gong Limin, Fadi Kassum, Khader Badarna, Nader Tarabeih, Nimmer Assy, Rona Fell, Hector Cohen, Munir Nashashibi, Alejandro Livoff, Muhammad Azab, George Habib, Dan Geiger, Omer Weissbrod, William Nseir
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Orphanet Journal of Rare Diseases
Subjects:
MYLK gene mutation
Aortic aneurysm and dissection
Genotype-phenotype
Online Access:http://link.springer.com/article/10.1186/s13023-018-0769-7

Internet

http://link.springer.com/article/10.1186/s13023-018-0769-7

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