Antithrombin Perfluorocarbon Nanoparticles Improve Renal Allograft Function in a Murine Deceased Criteria Donor Model

Background. Over 100 000 patients await renal transplantation and 4000 die per year. Compounding this mismatch between supply and demand is delayed graft function which contributes to short-term and long-term graft failures. Previously, we reported that thrombin-targeted perfluorocarbon nanoparticle...

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Bibliographic Details
Main Authors: Chandu Vemuri, MD, Gundumi A. Upadhya, MD, Batool Arif, MD, Jianluo Jia, MD, Yiing Lin, MD, PhD, Joseph P. Gaut, MD, PhD, Jawad Fazal, MD, Hua Pan, MD, Samuel A. Wickline, MD, William C. Chapman, MD
Format: Article
Language:English
Published: Wolters Kluwer 2018-09-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000817