Key Determinants of Human α-Defensin 5 and 6 for Enhancement of HIV Infectivity

Defensins are antimicrobial peptides important for mucosal innate immunity. They exhibit a broad spectrum of activity against bacteria, viruses, and fungi. Levels of α-defensins are elevated at the genital mucosa of individuals with sexually transmitted infections (STIs). Somewhat paradoxically, hum...

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Bibliographic Details
Main Authors: Kimyata Valere, Wuyuan Lu, Theresa L. Chang
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/9/244