Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature

Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature

Anticancer treatment efficacy is limited by the development of refractory tumor cells characterized by increased expression and activity of mechanisms promoting survival, proliferation, and metastatic spread. The present review summarizes the current literature regarding the use of the anthelmintic...

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Bibliographic Details
Main Authors: Andrea Emanuele Guerini, Luca Triggiani, Marta Maddalo, Marco Lorenzo Bonù, Francesco Frassine, Anna Baiguini, Alessandro Alghisi, Davide Tomasini, Paolo Borghetti, Nadia Pasinetti, Roberto Bresciani, Stefano Maria Magrini, Michela Buglione
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
chemoresistance
radioresistance
mebendazole
repurposing
cancer stem cells
cancer
CSC
anticancer
stemness
Online Access:https://www.mdpi.com/2072-6694/11/9/1284

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https://www.mdpi.com/2072-6694/11/9/1284

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