Restoring Blood Pressure in Hypertensive Mice Fails to Fully Reverse Vascular Stiffness

Restoring Blood Pressure in Hypertensive Mice Fails to Fully Reverse Vascular Stiffness

BackgroundHypertension is a well-established driver of vascular remodeling and stiffening. The goal of this study was to evaluate whether restoring normal blood pressure (BP) fully restores vascular stiffness toward that of normotensive controls.MethodsC57Bl6/J male mice received angiotensin II (ang...

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Bibliographic Details
Main Authors: Jochen Steppan, Sandeep Jandu, William Savage, Huilei Wang, Sara Kang, Roshini Narayanan, Daniel Nyhan, Lakshmi Santhanam
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
hypertension
vascular stiffness
pulse wave velocity
reversal
vascular smooth muscle cells
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00824/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00824/full

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