Prenyl Ammonium Salts--New Carriers for Gene Delivery: A B16-F10 Mouse Melanoma Model.

PURPOSE:Prenyl ammonium iodides (Amino-Prenols, APs), semi-synthetic polyprenol derivatives were studied as prospective novel gene transfer agents. METHODS:AP-7, -8, -11 and -15 (aminoprenols composed of 7, 8, 11 or 15 isoprene units, respectively) were examined for their capacity to form complexes...

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Main Authors: Emilia Grecka, Malgorzata Statkiewicz, Agnieszka Gorska, Marzena Biernacka, Monika Anna Grygorowicz, Marek Masnyk, Marek Chmielewski, Katarzyna Gawarecka, Tadeusz Chojnacki, Ewa Swiezewska, Maciej Malecki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4835110?pdf=render