Low-Cell-Number Epigenome Profiling Aids the Study of Lens Aging and Hematopoiesis

Understanding how chromatin modification regulates development and disease can be limited by available material. Despite recent progress, balancing high-quality and reliable mapping using chromatin-immunoprecipitation-based deep sequencing (ChIP-seq) remains a challenge. We report two techniques, re...

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Bibliographic Details
Main Authors: Xiaobin Zheng, Sibiao Yue, Haiyang Chen, Blake Weber, Junling Jia, Yixian Zheng
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715011432