Enantioselective nucleophilic difluoromethylation of aromatic aldehydes with Me3SiCF2SO2Ph and PhSO2CF2H reagents catalyzed by chiral quaternary ammonium salts

Background<p>Although the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO2CF2H and related reagents, there are still no reports on the enantioselective nucleophilic reactions.</p><p>Results</p><p>With a chiral quaternary am...

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Bibliographic Details
Main Authors: Chuanfa Ni, Fang Wang, Jinbo Hu
Format: Article
Language:English
Published: Beilstein-Institut 2008-06-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.3762/bjoc.4.21