Enantioselective nucleophilic difluoromethylation of aromatic aldehydes with Me3SiCF2SO2Ph and PhSO2CF2H reagents catalyzed by chiral quaternary ammonium salts
Background<p>Although the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO2CF2H and related reagents, there are still no reports on the enantioselective nucleophilic reactions.</p><p>Results</p><p>With a chiral quaternary am...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2008-06-01
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Series: | Beilstein Journal of Organic Chemistry |
Online Access: | https://doi.org/10.3762/bjoc.4.21 |