(<i>E</i>)-1-(Furan-2-yl)-(substituted phenyl)prop-2-en-1-one Derivatives as Tyrosinase Inhibitors and Melanogenesis Inhibition: An In Vitro and In Silico Study

(<i>E</i>)-1-(Furan-2-yl)-(substituted phenyl)prop-2-en-1-one Derivatives as Tyrosinase Inhibitors and Melanogenesis Inhibition: An In Vitro and In Silico Study

A series of (<i>E</i>)-1-(furan-2-yl)prop-2-en-1-one derivatives (compounds <b>1</b>–<b>8</b>) were synthesized and evaluated for their mushroom tyrosinase inhibitory activity. Among these series, compound <b>8</b> (2,4-dihydroxy group bearing benzylid...

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Bibliographic Details
Main Authors: Hee Jin Jung, Sang Gyun Noh, Il Young Ryu, Chaeun Park, Ji Young Lee, Pusoon Chun, Hyung Ryong Moon, Hae Young Chung
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
furan-chalcone
melanogenesis
molecular dynamics
tyrosinase inhibitor
Online Access:https://www.mdpi.com/1420-3049/25/22/5460

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https://www.mdpi.com/1420-3049/25/22/5460

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