Application of large volume injection for sensitive LC-MS/MS analysis of seven artificial sweeteners in surface waters

The combination of large volume injection and mixed-mode chromatography was performed for direct ultra-trace LC-MS/MS analysis of seven artificial sweeteners with varying physicochemical properties in surface water samples. • The injection volume was raised from 10 µL to 500 µL, while the overall an...

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Bibliographic Details
Main Authors: Jonas Henschel, Heiko Hayen
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221501612030354X