A pathogenic PSEN1 Trp165Cys mutation associated with early-onset Alzheimer’s disease

A pathogenic PSEN1 Trp165Cys mutation associated with early-onset Alzheimer’s disease

Abstract Background Presenilin-1 (PSEN1) is one of the causative genes for early onset Alzheimer’s disease (EOAD). Recently, emerging studies reported several novel PSEN1 mutations among Asian. We describe a male with EOAD had a pathogenic PSEN1 mutation. Case presentation A 53-year-old male present...

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Bibliographic Details
Main Authors: Vo Van Giau, Jung-Min Pyun, Jeewon Suh, Eva Bagyinszky, Seong Soo A. An, Sang Yun Kim
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Neurology
Subjects:
Pathogenic
PSEN1
Trp165Cys
Mutation
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s12883-019-1419-y

Internet

http://link.springer.com/article/10.1186/s12883-019-1419-y

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