Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias

Hereditary Spastic Paraplegias (HSPs) are a genetically diverse group of inherited neurological diseases with over 80 associated gene loci. Over the last decade, research into mechanisms underlying HSPs has led to an emerging interest in lysosome dysfunction. In this review, we highlight the differe...

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Bibliographic Details
Main Authors: Daisy Edmison, Luyu Wang, Swetha Gowrishankar
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
HSP
Online Access:https://www.mdpi.com/2076-3425/11/2/152