Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?

Dickkopf-1 (DKK1) is a secreted Wnt/β-catenin pathway antagonist involved in embryogenesis. It was first described 25 years ago for its function in head induction and limb morphogenesis. Since then, this protein has been widely studied in the context of active Wnt/β-catenin signalling during cellula...

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Bibliographic Details
Main Authors: Mélody Mazon, Delphine Masi, Madeleine Carreau
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/7/62