Isogarcinol is a new immunosuppressant.

Calcineurin (CN), a unique protein phosphatase, plays an important role in immune regulation. In this study we used CN as a target enzyme to investigate the immunosuppressive properties of a series of natural compounds from Garcinia mangostana L., and discovered an active compound, isogarcinol. Enzy...

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Bibliographic Details
Main Authors: Juren Cen, Mingshu Shi, Yanfang Yang, Yanxia Fu, Hailing Zhou, Mengqi Wang, Zhenyi Su, Qun Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681756?pdf=render