Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. R...

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Bibliographic Details
Main Authors: Valerie Wood, Antonia Lock, Midori A. Harris, Kim Rutherford, Jürg Bähler, Stephen G. Oliver
Format: Article
Language:English
Published: The Royal Society 2019-02-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180241