Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

Development of uterine endometrial receptivity for implantation is orchestrated by cyclic steroid hormone-mediated signals. It is unknown if these signals are necessary for oviduct function in supporting fertilization and preimplantation development. Here we show that conditional knockout (cKO) mice...

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Bibliographic Details
Main Authors: Wipawee Winuthayanon, Miranda L Bernhardt, Elizabeth Padilla-Banks, Page H Myers, Matthew L Edin, Fred B Lih, Sylvia C Hewitt, Kenneth S Korach, Carmen J Williams
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
oviduct
estrogen receptor
preimplantation embryo
fertilization
innate immunity
Online Access:https://elifesciences.org/articles/10453

Internet

https://elifesciences.org/articles/10453

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