Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.

Gastrointestinal (GI) mucosal damage is a devastating adverse effect of radiation therapy. We have recently reported that expression of Dclk1, a Tuft cell and tumor stem cell (TSC) marker, 24h after high dose total-body gamma-IR (TBI) can be used as a surrogate marker for crypt survival. Dietary pec...

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Bibliographic Details
Main Authors: Sripathi M Sureban, Randal May, Dongfeng Qu, Parthasarathy Chandrakesan, Nathaniel Weygant, Naushad Ali, Stan A Lightfoot, Kai Ding, Shahid Umar, Michael J Schlosser, Courtney W Houchen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4536042?pdf=render