Role of adenosine in the antiepileptic effects of deep brain stimulation

Role of adenosine in the antiepileptic effects of deep brain stimulation

Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy remain elusive. As adenosine modulates neuronal excitability and seizure activity in animal models, we hypothes...

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Bibliographic Details
Main Authors: Maisa eMiranda, Clement eHamani, Antonio-Carlos eAlmeida, Beatriz eAmorim, Carlos eMacedo, Maria Jose eFernandes, Jose eNobrega, Mayra eAarao, Ana Paula eAntonio, Antonio eRodrigues, Monica L Andersen, Sergio eTufik, Luiz E Mello, Luciene eCovolan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Adenosine
Deep Brain Stimulation
Epilepsy
Seizures
Thalamus
anterior nucleus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00312/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00312/full

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