HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.
Enterovirus 71 (EV71) is an RNA virus that causes hand-foot-mouth disease (HFMD), and even fatal encephalitis in children. Although EV71 pathogenesis remains largely obscure, host immune responses may play important roles in the development of diseases. Recognition of pathogens mediated by Toll-like...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-08-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5595348?pdf=render |