A novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy

The role of T cells in controlling human cancers is well known. Their success requires continued persistence in vivo and efficient trafficking to tumor sites, requirements shared by other effectors such as Natural Killer (NK) cells. To date, cytokine IL2 remains the only clinically approved cytokine...

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Bibliographic Details
Main Authors: Hong Xu, Ilia N. Buhtoiarov, Hongfen Guo, Nai-Kong V. Cheung
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1893500