Glucosamine-paracetamol spray-dried solid dispersions with maximized intrinsic dissolution rate, bioavailability and decreased levels of in vivo toxic metabolites

Glucosamine-paracetamol spray-dried solid dispersions with maximized intrinsic dissolution rate, bioavailability and decreased levels of in vivo toxic metabolites

Ahmed Mahmoud Abdelhaleem Ali,1,2 Ahmed Khames,1,2 Majed Mansour Alrobaian,1 Mohammad Hamaidi,3 Mohammed AS Abourehab4,5 1Department of Pharmaceutics, Faculty of Pharmacy, Taif University, Taif, Kingdom of Saudi Arabia; 2Department of Pharmaceutics, Beni-Suef University, Beni-Suef, Egypt; 3Departme...

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Bibliographic Details
Main Authors: Ali AMA, Khames A, Alrobaian MM, Hamaidi M, Abourehab MAS
Format: Article
Language:English
Published: Dove Medical Press 2018-09-01
Series:Drug Design, Development and Therapy
Subjects:
Glucosamine
Paracetamol
Pharmacokinetics
Reduced hepatotoxicity
Solid dispersions
Spray drying
Online Access:https://www.dovepress.com/glucosamine-paracetamol-spray-dried-solid-dispersions-with-maximized-i-peer-reviewed-article-DDDT

Internet

https://www.dovepress.com/glucosamine-paracetamol-spray-dried-solid-dispersions-with-maximized-i-peer-reviewed-article-DDDT

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