Melting Down Protein Stability: PAPS Synthase 2 in Patients and in a Cellular Environment

Melting Down Protein Stability: PAPS Synthase 2 in Patients and in a Cellular Environment

Within the crowded and complex environment of the cell, a protein experiences stabilizing excluded-volume effects and destabilizing quinary interactions with other proteins. Which of these prevail, needs to be determined on a case-by-case basis. PAPS synthases are dimeric and bifunctional enzymes, p...

Full description

Bibliographic Details
Main Authors: Oliver Brylski, Simon Ebbinghaus, Jonathan W. Mueller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
sulfation pathways
PAPS synthase
quinary interaction
excluded volume effect
ligand stabilization
enzyme storage complex
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00031/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2019.00031/full

Similar Items