Flexible analysis of digital PCR experiments using generalized linear mixed models

Flexible analysis of digital PCR experiments using generalized linear mixed models

The use of digital PCR for quantification of nucleic acids is rapidly growing. A major drawback remains the lack of flexible data analysis tools. Published analysis approaches are either tailored to specific problem settings or fail to take into account sources of variability. We propose the general...

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Bibliographic Details
Main Authors: Matthijs Vynck, Jo Vandesompele, Nele Nijs, Björn Menten, Ariane De Ganck, Olivier Thas
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Biomolecular Detection and Quantification
Subjects:
Digital PCR
Statistics
Data analysis
Mixed models
Replicates
Quantification
Online Access:http://www.sciencedirect.com/science/article/pii/S2214753516300146

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http://www.sciencedirect.com/science/article/pii/S2214753516300146

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