An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

BACKGROUND: The artemisinin-based combination treatment (ACT) of dihydroartemisinin (DHA) and piperaquine (PQP) is a promising novel anti-malarial drug effective against multi-drug resistant falciparum malaria. The aim of this study was to show non-inferiority of DHA/PQP vs. artesunate-mefloquine (A...

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Bibliographic Details
Main Authors: Neena Valecha, Aung Pyae Phyo, Mayfong Mayxay, Paul N Newton, Srivicha Krudsood, Sommay Keomany, Maniphone Khanthavong, Tiengkham Pongvongsa, Ronnatrai Ruangveerayuth, Chirapong Uthaisil, David Ubben, Stephan Duparc, Antonella Bacchieri, Marco Corsi, Bappanad H K Rao, Prabash C Bhattacharya, Nagesh Dubhashi, Susanta K Ghosh, Vas Dev, Ashwani Kumar, Sasithon Pukrittayakamee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912766?pdf=render

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http://europepmc.org/articles/PMC2912766?pdf=render

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