Mapping cortical degeneration in ALS with magnetization transfer ratio and voxel-based morphometry.

Pathological and imaging data indicate that amyotrophic lateral sclerosis (ALS) is a multisystem disease involving several cerebral cortical areas. Advanced quantitative magnetic resonance imaging (MRI) techniques enable to explore in vivo the volume and microstructure of the cerebral cortex in ALS....

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Bibliographic Details
Main Authors: Mirco Cosottini, Paolo Cecchi, Selina Piazza, Ilaria Pesaresi, Serena Fabbri, Stefano Diciotti, Mario Mascalchi, Gabriele Siciliano, Ubaldo Bonuccelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23874570/?tool=EBI