Molecular investigations of PenA-mediated beta-lactam resistance inBurkholderia pseudomallei

Molecular investigations of PenA-mediated beta-lactam resistance inBurkholderia pseudomallei

Burkholderia pseudomallei is the etiological agent of melioidosis. Because of the bacterium’s intrinsic resistance and propensity to establish latent infections, melioidosis therapy is complicated and prolonged. Newer generation b-lactams, specifically ceftazidime, are used for acute phase therapy...

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Bibliographic Details
Main Authors: Drew A Rholl, Krisztina M Papp-Wallace, Andrew P Tomaras, Michael L Vasil, Robert A Bonomo, Herbert P Schweizer
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
beta-Lactams
Burkholderia pseudomallei
Melioidosis
antibiotic resistance
beta-lactamase
TAT secretion
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00139/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00139/full

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