Hypermethylation of the 16q23.1 Tumor Suppressor Gene ADAMTS18 in Clear Cell Renal Cell Carcinoma

Hypermethylation of the 16q23.1 Tumor Suppressor Gene ADAMTS18 in Clear Cell Renal Cell Carcinoma

To identify tumor suppressor genes (TSGs) silenced by hypermethylation and discover new epigenetic biomarkers for early cancer detection. ADAMTS18, located at 16q23.1, has been reported to be a critical TSG in multiple primary tumors; however, this has not yet been verified in clear cell renal cell...

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Bibliographic Details
Main Authors: Ben Xu, Lian Zhang, Cheng Luo, Yan Qi, Yun Cui, Jian-Ming Ying, Qian Zhang, Jie Jin
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
hypermethylation
ADAMTS18 gene
clear cell renal cell carcinoma
tumor suppressor gene
Online Access:http://www.mdpi.com/1422-0067/16/1/1051

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http://www.mdpi.com/1422-0067/16/1/1051

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