Multi-target directed donepezil-like ligands for Alzheimer's disease

Multi-target directed donepezil-like ligands for Alzheimer's disease

Alzheimer's disease (AD), the most common form of adult onset dementia, is an age-related neurodegenerative disorder characterized by progressive memory loss, decline in language skills and other cognitive impairments. Although its etiology is not completely known, several factors including def...

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Bibliographic Details
Main Authors: Mercedes eUnzeta, Gerard eEsteban, Irene eBolea, Wieslawa Agnieszka Fogel, RONA R. RAMSAY, Moussa B.H. Youdim, Keith F Tipton, Jose eMarco-Contelles
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Neuroscience
Subjects:
Oxidative Stress
Alzheimer’s disease
donepezil
Multi-target-directed ligands
anti-β-Amyloid aggregation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00205/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00205/full

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