The Relationship of Immune Cell Signatures to Patient Survival Varies within and between Tumor Types.

Enhancing pre-existing anti-tumor immunity leads to therapeutic benefit for some patients, but why some tumors are more immunogenic than others remains unresolved. We took a unique systems approach to relate patient survival to immune gene expression in >3,500 tumor RNAseq profiles from a dozen t...

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Bibliographic Details
Main Authors: Peter S Linsley, Damien Chaussabel, Cate Speake
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580625?pdf=render